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From techcrunch.com review

we found that Ning provides the best platform for getting up good-looking, sophisticated social networks with minimal effort.

KickApps provides the best platform for integrating social networking components into existing websites.

CrowdVine and Haystack are viable options for organizations that are looking for simple social networks to improve personalized communication online.

CollectiveX is most suitable for existing groups that want to collaborate online.

And GoingOn provides a promising hybrid solution with capabilities shared by both Ning and KickApps.

More details on each are below.